Summary of Systematic Review

Monitoring for Postnatal Hearing Loss Using Risk Factors: A Systematic Literature Review
Beswick, R., Driscoll, C., et al. (2012).
Ear & Hearing, 33(6), 745-756.

This review meets the criteria for a high-quality evidence-based systematic review.

Indicators of Review Quality:

The review states a clearly focused question or aim Yes
Criteria for inclusion of studies are provided Yes
Search strategy is described in sufficient detail for replication Yes
Included studies are assessed for study quality Yes
Quality assessments are reproducible Yes
Characteristics of the included studies are provided Yes*

*Available through supplemental online content

This is a systematic review of the peer- and non-peer-reviewed published literature investigating the effectiveness of using a risk-factor registry for targeted surveillance to identify hearing loss after the newborn hearing screen.

Question(s)/Aim(s) Addressed:

  1. What risk factors are being used to determine referral for assessment of postnatal hearing loss?

  2. What are the referral rates for monitoring assessments for postnatal hearing loss in infants?

  3. What is the relationship between risk factors for postnatal hearing loss and diagnostic findings from monitoring assessments?

  4. Are there any other protocols or approaches available that are more accurate, efficient, and cost-effective than the use of risk-factor registries?

Children identified with permanent bilateral or unilateral hearing loss after passing the hearing screening or assessment at birth.

Targeted surveillance based on hearing loss risk factors.

Number of Studies Included:

Years Included:


Permanent Childhood Hearing Loss

  • Assessment/Screening

    • Screening

      • Risk Factors/Surveillance

        • Among risk-factor registries, the most commonly used risk factors included: gestational age (GA), low birthweight (LBW), craniofacial anomalies, respirator support, aminoglycoside use, and TORCH infections (Toxoplasmosis, other infections, Rubella, Cytomegalovirus [CMV], and Herpes simplex virus).

        • Risk factors strongly associated with hearing loss were: CMV, extracorporeal membrane oxygenation (ECMO), congenital diaphragmatic hernia, and persistent pulmonary hypertension of the newborn (PPHN).

        • Risk factors with limited or no association with hearing loss included LBW, preauricular skin tags and ear pits(PSEP), neonatal toxoplasmosis.

        • No studies comparing risk-factor registries to alternative protocols for detecting postnatal hearing loss were found.

Sponsoring Body:
Not stated.

Deafness, Hearing Loss

» Access the Review